TNN Vitamin B12
Vitamin B12, also known as cobalamin, is a polycyclic compound containing 3-valent cobalt. The four reduced pyrrole rings are joined together to form the Gulin macrocycle (similar to porphyrin), which is the only vitamin-containing metal element. Vitamin B12 is a red crystalline powder, odorless and tasteless. Slightly soluble in water and ethanol. It is most stable in slightly acidic conditions with a pH value of 4.5 ~ 5.0. Decomposes in strong acid (pH).
Description
Product Parameter
Cyanocobalamin pure
| Test element | Specification |
| Appearance | Dark red crystal or dark red crystal |
| Identification A | UV: absorption maxima at 278±1 nm, 361±1 nm and 550±2 nm. |
| A361nm /A278nm: 1.70-1.90 | |
| A361nm / A550nm: 3.15-3.40 | |
| Identification B |
TLC: The main spot on the chromatogram obtained with the test solution is similar in position, color and size to the main one spot in a chromatogram obtained using a standard solution. |
| Drying losses | Less than or equal to 12.0% |
| Try | 96.0%~102.0% |
| Residuals | Impurities Tptal Less than or equal to 3.0% |
| Residual solvents | Acetone Less than or equal to 5000 p/pm |
| Total aerobic bacteria | Less than or equal to 1000 cfu/g |
| Mold, yeast | Less than or equal to 100 cfu/g |
Mecobalamin Pure
| Test element | Specification |
| Appearance | Dark red crystal or dark red crystal |
| Identification |
UV: Compare the spectrum with the reference spectrum, both exhibit spectra similar absorption intensities at the same wavelengths |
| Cobalt: JP compliant | |
| Transparency and color of the solution | Transparent and red color solution |
| Try | 98.5%-101.0% |
| Water | Less than or equal to 11.5% |
| Related substances | Each peak area, except mecobalamin, represents no more than 0.5% of the peak area of mecobalamin. |
| The total peak area except for mecobalamin is no more than 2.0% | |
| Acetone | Less than or equal to 5000rr/s |
| Total number of aerobic microbes | Less than or equal to 1000 cfu/g |
Other characteristics: Cyanocobalamin Feed grade 0,1%,1%Cyanocobalamin Food grade 1%,2%,5%
Product details
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Cyanocobalamin CAS Number:68-19-9 EINEX number:200-680-0 Place of Origin: China (Mainland) Grade Standard: Pharmaceutical Grade, Feed Grade, Food Grade Brand Name: TNN Model Number: BP USP EP Purity: 0,1%,1%,2%,5%,99% |
| Mecobalamin CAS Number:13422-55-4 EINECS number:236-535-3 Place of Origin: China (Mainland) Grade Standard: Pharmaceutical Grade, Food Grade Brand Name: TNN Model Number: JP Purity:99% |
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Packaging and delivery
0.5kg/tin,1kg/tin
Application
1. Promotes methyl transfer
2. Promote the development and maturation of red blood cells, bring the body’s hematopoietic function to a normal state, prevent pernicious anemia; Maintaining a Healthy Nervous System
3. In coenzyme form, it can increase the utilization of folic acid and promote the metabolism of carbohydrates, fats and proteins
4. It can activate amino acids, promote nucleic acid biosynthesis, and promote protein synthesis. It plays an important role in the growth and development of babies
5. Metabolize fatty acids so that fats, carbohydrates and proteins can be properly used by the body
6. Eliminate irritability, concentrate, improve memory and sense of balance
7. It is an essential vitamin for healthy nervous system function and is involved in lipoprotein formation in nerve tissue
First, improve the utilization rate of folic acid, synthesize methionine (synthesized by homocysteine) and choline along with folic acid, and synthesize cyanocobalamin through the production of purines and pyrimidines, such as methylcobalamin and coenzyme B12, which are involved in the methylation process of many important compounds. When vitamin B12 is insufficient, the methyl group transfer activity from methyltetrahydrofolate is reduced, making folic acid an unusable form, resulting in folate deficiency.
The second is to support nerve myelin metabolism and function. Vitamin B12 deficiency can cause neurological disorders, spinal cord degeneration and serious psychiatric symptoms. Vitamin B12 deficiency can lead to peripheral neuritis. Early manifestations of vitamin B12 deficiency in children are abnormal mood, dull expression, slow reaction and finally lead to anemia.
Thirdly, they promote the development and maturation of red blood cells. Methylmalonyl coenzyme A is converted to succinyl coenzyme A, which participates in the tricarboxylic acid cycle. Succinyl coenzyme A is associated with heme synthesis.
Fourth, vitamin B12 is also involved in the synthesis of deoxynucleic acid (DNA), the metabolism of fats, carbohydrates and proteins, and also increases the synthesis of nucleic acid and protein.
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